Breast cancer is the most common cancer diagnosed in women
and is the second most common cause of cancer-related death, in women, in North
America. Approximately 25% of all newly diagnosed breast
cancer cases occur among women younger than 50 years of age. Breast cancer
is one of the most treatable cancers.
Recent advancements in breast cancer screening, surgical
techniques, adjuvant radiation and systemic therapy have resulted in
substantial reduction in risk of recurrence and overall- and breast
cancer-related mortality. Nevertheless, the cancer treatments cause many acute
and chronic adverse effects and are associated with significant impact on
quality of life.
Premenopausal women with breast cancer are suffered from
many cancer treatment symptoms including fatigue, hot flashes, insomnia, pain,
impaired memory, weight gain, menstrual disturbance, vaginal dryness, and are
faced with the challenges of sexual dysfunction and impaired fertility.
The symptoms are more pronounced during cancer treatment but
can last for several years after completion of the therapy. In this paper we
discuss the impact of surgery and adjuvant therapy in reproductive and sexual
health of premenopausal women with breast cancer and highlight various
treatment options.
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