Spontaneous abortion and the associated
factors are considered to be crucial concerns for the researchers and
physicians to study. It is stated as the spontaneous loss of a fetus before the
20th week of pregnancy.
A systematic review showed that 30-50% of
conceptions end in spontaneous abortion which affect 0.5-3% of women in the
reproductive age group. Studies have shown that spontaneous abortions
can occur as a consequence of genetic factors, infections, diabetes,
hyperprolactinemia, thyroid autoimmunity and oxidative stress.
Reactive oxygen species (ROS) is a collective
term for oxygen free radicals (i.e., nitric oxide, superoxide) and non-radical
oxygen (i.e., hydrogen peroxide, singlet oxygen) compounds which are produced
in low concentrations in the body to maintain the normal cellular homeostasis.
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