During the menopause, oestrogen deficiency
brings about changes in the lipid profile which increase the cardiovascular
(CV) risk. The use of food supplements together with a healthy
lifestyle and a varied, balanced diet is a logical approach for improving CV
disease prevention.
A combination of nutraceuticals (EL) based on
berberine (a natural extract that reduces total cholesterol and triglycerides),
soya isoflavones (SI), Lactobacillus sporogenes and vitamin D3 was compared
with the same formulation without berberine (E) in menopausal women with
borderline dyslipidaemia.
Randomised, controlled, parallel-group
multicenter study in menopausal women with Tot-C >200 and <260 mg/dl on a
controlled low-fat diet or not on treatment with lipid-lowering agents. The
study treatments were: 1 tablet of EL (Estromineral Lipid) or E (Estromineral®)
daily by mouth for 3 months. Typical menopausal symptoms, CV and metabolic
parameters were evaluated at baseline and at the end of treatment.
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